| Innovative therapeutic tools for rheumatic diseases
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| Technical Description : |
| This is a method for obtaining a population of chondrocytes, said method comprising a step of culturing pluripotent or multipotent stem cells with a culture medium comprising Wnt6 or a derivative thereof. The invention also relates to the use of Wnt6 or a derivative thereof for the treatment of osteo-articular pathologies, and/or for tissue reconstitution or regeneration, and/or the inhibition of the differentiation of mature chondrocytes to hypertrophic chondrocytes.. |
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| Potential applications : |
Treatment of osteo-articular pathologies by tissue reconstitution or regeneration (chondrocytes population).
Inhibition of the differentiation of mature chondrocytes to hypertrophic chondrocytes, adipocytes or osteoblasts. |
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| Intellectual property : |
| PCT/FR2009/0250768 filed by Inserm April 24, 2009 |
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