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		<title>Technology Offers  - OSEO</title>
		<description>The 10 newest offers</description>		<link>http://www.technologie.oseo.fr</link>		<item>
			<title><![CDATA[METHOD FOR MONITORING HEALTH AND WELLNESS]]></title>
			<description><![CDATA[A lot of devices are designed to evaluate health or wellness. However, these devices are based on fast variation and can produce false alarms.
This new method is original because the environment is taken into account to detect slow grift of health condition. An algorithm combines data from several sensors with physiological parameters to deduce required indicators. Thus, even without any warning symptoms, it is possible to anticipate a degradation ot health condition or wellness. Besides medical applications, this method is an innovative tool for sportmen/women to monitor performances and optimize trainings. 
> Health monitoring
 
> e-health
 
> Sports : monitoring performances 
 
> Sports : Improvement and customization of trainings 
 
 

> The risk of false alarms is reduced
 
> The degradation of health condition / wellness is detected early
 
> The environment is taken into account
 
 
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			<pubDate><![CDATA[Tue, 31 Aug 2010 00:20:08 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/1/1_3/1_3_1/147?lang=ang</link>
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			<title><![CDATA[ACID TREATMENT OF A WASTE CONTAINING ASBESTOS]]></title>
			<description><![CDATA[&nbsp;
Asbestos is a fibrous, naturally occurring material commonly found in buried demolition debris and building materials. It is this fibrous structure that made it a popular insulating material. Asbestos is known to cause cancer in humans and especially lung cancer by inhalation. The toxicity of asbestos is due to the fibrous structure of the material rather than its chemical properties.
In most developed countries, asbestos is typically disposed of as hazardous waste in landfill sites. But storage capacities are not unlimited. Asbestos-containing materials disposal costs are quite expensive and are expected to rise substantially.
Asbestos can also be recycled by vitrification process. Plasma arc destruction of asbestos containing materials could provide an effective solution to the asbestos disposal problem. The high temperatures achievable with plasma arc torch technology can melt and vitrify asbestos and transform asbestos containing materials a chemically inert, glasslike residue. This method can be an environmentally safe, efficient, and effective method of destroying and vitrifying asbestos fibres. But it also expensive and has a treatment capacity rather small. 
Inventors have found a process, simple, rapid, cheap and efficient to convert asbestos fibres into non-hazardous products, which presents an advantageous alternative to vitrification process, to recycle asbestos containing materials.&nbsp;

The present invention relates to a process for treating a waste containing asbestos, comprising a step in which the asbestos contained in said waste is dissolved by reacting this waste with an acid other than hydrofluoric acid, preferably with hydrochloric acid, at a temperature of at least 125 °C and at a pressure greater than 0.2 MPa (2 bar), and in which: the asbestos included in the treated waste is an asbestos of amphibole type;and/or the solution obtained at the end of the acid dissolution of the asbestos is reused, for example for the synthesis of apatites.
BENEFITS
The invention has the following advantages:
-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Its efficient on flocked asbestos and asbestos cement wastes;
-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The reaction is complete with all types of asbestos;
-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The process is rather inexpensive and with easy scale-up;
-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The reaction product can be used for different applications like magnesium recovery, synthesis of apatites. These by-products can be sold.
Asbestos Wastes disposal and valorisation


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			<pubDate><![CDATA[Sat, 21 Aug 2010 00:21:02 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/10/10_2/10_2_1/01964_01?lang=ang</link>
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			<title><![CDATA[Integration platform for Web services access composition and data sharing in a distributed environment]]></title>
			<description><![CDATA[The platform allows to integrate distributed data sources having proprietary interfaces by using the Web services technology. It uses  powerful algorithms to compose Web services access to data in order to answer multisource users queries in a totally automatic and transparent way. Heterogenic data sources access is made easier  to any user through composite Web services while complex mechanisms of composition, homogenisation, data recovery and query rewriting are masked.
- Customer Relationship Management / Enterprise Resource Planning scenarii (to integrate companies sources and offer a uniform interface for all data)
- Geolocation, location based services on mobile phones
- E-government (government to citizen, to customer, to business, to employees, to government)
- Telehealth, telemedicine
- E-learning

Use of this new platform generates:
- Applications composition for heterogenic and distributed data integration
- Quality of service
- Costs and time limit reduction
- New revenue stream
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			<pubDate><![CDATA[Thu, 29 Jul 2010 09:53:21 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/1/1_2/1_2_10/lst05soft?lang=ang</link>
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			<title><![CDATA[New targeted treatment against cancer]]></title>
			<description><![CDATA[The ALK receptor tyrosine kinase was identified as part of a protein fusion derived from a chromosomal translocation. Constitutive overexpression and activation of the X-ALK fusion protein is a key oncogenic event that maintains a persistent mitogenic signal that finally leads to tumour formation, survival and proliferation. Alk is stucturally altered through translocations of point mutations in Lymphomas and lung cancer.  The laboratory has designed and developed four chemical scaffolds that are able to inhibit ALK activity with IC50 in the nanomolar-low micromolar range. Within three of the four chemical classes, five lead compounds to be further optimized have been identified.
Cancer treatment
Chemotherapy
5 lead compounds inhibiting ALK kinase activity were identified in vitro.
ALK fusion proteins represent a very promising target for therapeutic intervention against several cancer types. ALK inhibitors identified by the laboratory are specific and show IC50 in the nanomolar-low micromolar range.
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			<pubDate><![CDATA[Wed, 28 Jul 2010 11:58:00 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/6/6_1/6_1_4/lst16bio?lang=ang</link>
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			<title><![CDATA[Plasfibres: a simulation software tool of textile draping and for LCM composites]]></title>
			<description><![CDATA[Plasfibres is a simulation software of composites reinforcements  draping in Liquid Composites Moulding processes and of fibrous media such as textiles in general.
The software allows simulations according to geometry and given limit conditions. Internal deformations are important for non developable shapes. The software allows to locate fibers positions at the end of draping. It leans on finite elements specific to shells without liberty degrees in rotation in order to gain digital efficiency. Special tests have been defined and led to international benchmarks. Plasfibres directly uses material results obtained by these tests: biaxial traction, shearing by Bias test and cantilever type bending.
- Composites simulation by Liquid Composite Moulding (LCM) : army, aeronautics
- Clothing industry : technical textiles, design
With Plasfibres, today it is possible to simulate 16 layers for simple shapes and 8 layers for complex ones. Developments are possible according to processes to simulate.
- The software allows to simulate various efforts and their position while avoiding developing steps of textile draping processes by error assays
- The software allows to calculate several layers and simulate folds appearance.
- Fibers positioning
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			<pubDate><![CDATA[Wed, 28 Jul 2010 11:49:12 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/1/1_2/1_2_16/lst04soft?lang=ang</link>
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			<title><![CDATA[New reinforcement system for reinforced concrete structures]]></title>
			<description><![CDATA[The new system of reinforcement is developed by bonding the reinforcement elements made of ceramic matrix reinforced by Fiber Reinforced Polymer (FRP) pultruded rebars. Quantity of material used is reduced. Mechanical performance of the reinforced concrete structures are increased in service and at failure. Bending stiffness is improved thanks to increased inertia of the flat of strengthening. In addition, reinforcement ends geometry can be adapted to limit delamination phenomena.
Repair and reinforcement of reinforced concrete structures (beam and slab):
- Civil engineering
- Public buildings and works sector
A prototype proving the performance has been developed.
- low cost
- more efficient and compatible materials with the environmental criteria and sustainable development
- reinforcement protected against fire
- overstress reduction
- high resistance and module 
- increased inertia
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			<pubDate><![CDATA[Wed, 28 Jul 2010 11:34:54 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/2/2_6/2_6_1/lst03env?lang=ang</link>
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			<title><![CDATA[VODKA : Low cost, contactless Position Sensing Device   for optical tracking, docking, and stabilization of UAVs]]></title>
			<description><![CDATA[• Position 
Sensing Device 
(PSD), 
• Non-emissive, 
visual sensor,  
• Visual tracking,         
• Vision based 
autopilots 
• Cable & power 
lines detectors 
• Crash 
avoidance 
- Autopilot for UAVs, MAVs, ROVs, UGVs, and spatial vehicles: drift 
free system stabilizer, precise hovering and precise docking.  
- Drift correction: can compensate for the natural drift of miniature IMUs 
- Cable detector for manned or unmanned aerial  and underwater 
vehicles  
- Automatic crash avoidance 
We built a sensor prototype that measures the position of a contrasting object with a high accuracy, within a wide illuminance range and for a wide range of contrast. The sensor was tested onboard a 100-gram aerial robot that achieved optical target tracking with a high precision.  
Advantages existing systems/VODKA 
Weight: Heavy/Lightweight 
Size: Bulky/Compact 
Price: High/Low 
Power Consumption: High/Low 
Computation: Intensive/Lean 
Resistance to vibration: Medium/High 
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			<pubDate><![CDATA[Tue, 27 Jul 2010 14:18:56 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/1/1_2/vp_27?lang=ang</link>
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			<title><![CDATA[New antigen for prevention and diagnosis of pregnancy-associated malaria ]]></title>
			<description><![CDATA[Pregnancy-associated malaria, caused by the parasite Plasmodium falciparum, is a major public health issue in areas of endemic malaria. This disease is associated with dramatic adverse effects on foetal growth, leading to low weight of newborns or even neonatal deaths as well as maternal anaemia.
Immunoprophylaxis would overcome the various problems arising from the chemoprophylactic methods currently used for malaria prevention in pregnant women: complicated logistics of medicine distribution; delayed first visit of health care services by pregnant women living in the tropics and expansion of parasite resistance to various medicines.
An IRD research team established a differential study to identify genes overexpressed by placental parasites. Two genes were shown to have a higher level of expression in parasites infecting pregnant women than those in non-pregnant women or children: the gene var2csa, identified in a previous study, and the gene PFI1785w.

The product of this gene is an excellent candidate for obtaining candidate peptides for prevention and diagnosis of malaria infection in pregnant women.
Research results
.Use of PFI1785w overcomes the disadvantages of the current candidate vaccine, VAR2CSA (high molecular weight and high degree of polymorphism).
.This molecule shows a very high conservation level between several Plasmodium falciparum isolates and lineages and it is specifically recognized by serum samples from pregnant women.
.Strongly immunogenic.

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			<pubDate><![CDATA[Wed, 21 Jul 2010 17:03:43 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/6/ot5?lang=ang</link>
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			<title><![CDATA[Candidate anti-Leishmania vaccines and methods for obtaining them]]></title>
			<description><![CDATA[Leishmaniases are parasitic infections caused by protozoa of the genus Leishmania. They constitute a serious public health problem. A team of IRD researchers has developed a process and a culture medium that are optimized for obtaining excretion-secretion polypeptides of these parasites. This method made possible the identification of several peptides in the culture medium supernatant, which were subsequently characterized. Some of them correspond to a virulence factor of this species, coded by a single gene. Parasites transfected by an antisense construction of this gene completely lost the expression of this gene’s product and showed a sharp loss of their infective power of canine macrophages in vitro. These results confirmed the effectiveness of this approach for identifying virulence genes in protozoa of the genus Leishmania, and the use of identified sequences for obtaining avirulent strains of protozoa. The strains obtained, and the proteins coded by the virulence genes that were identified, are ideal tools for obtaining anti-leishmaniasis vaccines.
This technology can be used to obtain candidate vaccines for therapeutic or prophylactic objectives, targeted against parasites of the Trypanosomatidae family. 
It involves tools well adapted for the control of parasitic diseases such as leishmaniasis that affect pet animals, communities in the developing countries and patients suffering from Aids anywhere in the world.
A candidate vaccine is currently being tested in dogs.
.A vaccine against these diseases will be a major advantage considering the existing barriers that strongly hinder the use of most chemical preparations: problems of medicine administration and long duration of certain treatments, high cost, toxicity and a rising number of resistant parasites.
.The use of strains whose virulence has been reduced appears to be an effective approach because they are rapidly killed in the host, which provides a source of antigens effective in triggering an immune response

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			<pubDate><![CDATA[Wed, 21 Jul 2010 16:45:59 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/6/ot3?lang=ang</link>
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			<title><![CDATA[Protozoan strains with reduced virulence for ]]></title>
			<description><![CDATA[The development of an effective vaccine against parasitic diseases caused by protozoa of the Trypanosomatidae family (human and canine leishmaniasis, Chagas disease, sleeping sickness) is a major challenge. An IRD research team identified genes coding for virulence factors in Leishmania, and has developed protozoan strains in which one of these genes is inactivated.

This gene inactivation induces the arrest of parasitic proliferation in the vertebrate host (by blocking the cell cycle in G0/G1), and therefore the ability to induce a chronic infection. It was shown that the in vivo and in vitro virulence of these strains is lower than the wild type strain: although the mutant clones are infectious in a mouse model of the disease, the parasite load gradually decreases and no living parasites are detected some weeks after infection. These results provide proof of concept that clones whose virulence has been reduced can be used for developing a vaccine strategy against human and canine leishmaniasis.

These strains can be used as candidate vaccines, for therapeutic or prophylactic purposes, against parasites of the Trypanosomatidae family. They are highly advantageous tools for control of parasitic diseases such as leishmaniasis of pet animals, of people in the developing countries, and patients suffering from Aids throughout the world.
Proof of concept
.An effective vaccine against this disease is a major advantage considering the current barriers hindering the use of most chemical preparations: medicine administration difficulties, length of treatment, high cost, toxicity, as well as the emergence of resistant strains.
.The use of strains whose virulence has been attenuated is an effective and original approach for developing vaccines because the parasites are killed in the host, delivering antigens to trigger and target an effective anti-Leishmania immune response.

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			<pubDate><![CDATA[Wed, 21 Jul 2010 16:29:35 +0200]]></pubDate>
			<link>http://www.technologie.oseo.fr/repertoires_d_offres/6/ot1?lang=ang</link>
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